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Our Mission

The mission of the Veterans Research and Education Foundation of St. Louis is to improve the health and well-being of Veterans through research and education conducted within the VA St. Louis Health Care System.

Best Endovascular vs. Best Surgical Therapy in Patients with Critical Limb Ischemia

This research study is enrolling participants diagnosed with peripheral artery disease (PAD) that has caused critical limb ischemia (CLI). In CLI, arteries that deliver blood to the leg and foot are narrowed or blocked by plaques buildup and can cause pain, leg ulcerations, and can sometimes lead to gangrene and loss of the leg. There are two different ways to increase the blood flow in CLI; open surgery and endovascular treatment. The purpose of the study is to learn about which therapy is more suitable for those patients who are candidates for both open surgery and endovascular treatment, and to provide information regarding cost effectiveness of the two different types of treatment.

PI: Dr. Mohamed Zayed

Study Coordinator: Kelley Chadwick-Mansker

This study is now closed to enrollment.