Veteran's Research and Education Foundation Logo

Our Mission

The mission of the Veterans Research and Education Foundation of St. Louis is to improve the health and well-being of Veterans through research and education conducted within the VA St. Louis Health Care System.

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Prevention of stroke involves managing and treating risk factors. Most strokes are caused when blood flow to a portion of the brain is blocked. One place this often happens is in the carotid artery. This blockage is called atherosclerosis or hardening of the arteries.

The purpose of this trial is to determine the best way to prevent strokes in people who have a high amount of blockage of their carotid artery but no stroke symptoms related to that blockage. Each eligible participant will be evaluated to determine which procedure(s) is best for him/her. All participants will receive intensive medical treatment. In addition, participants will be randomized to receive the selected procedure or not.

PI: Dr. Emad Zakhary

Study Coordinator / Research Nurse: Peggy Donovan

This study is currently enrolling. To learn more about CREST 2 and how you can join contact our research office at (314) 289-7690